Bordetella pertussis Polymorphism and Pertussis Vaccines

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Bordetella pertussis polymorphism and pertussis vaccines.

The topic of the article by Bottero et al. (1) is an important one, a bacterial vaccine for a preventable disease, pertussis. Many articles have been published on the subject in the last 10 years (for a review, see reference 6). In their study, Bottero et al. neither followed the recommendations of consensus meetings nor used published nomenclature. Furthermore, they compared vaccines that cann...

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Bordetella pertussis and pertussis vaccines.

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Acellular pertussis vaccines and complement killing of Bordetella pertussis.

Antibody-dependent complement killing of Bordetella pertussis after immunization with a three-component acellular pertussis vaccine was characterized. Postimmunization activity was unchanged for about half of the adult vaccine recipients. The responses of the other individuals were complex, with evidence of both beneficial and antagonistic responses occurring, sometimes in the same individual.

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Regulation of pertussis toxin and lipopolysaccharide levels of Bordetella pertussis 134 in response to modulators

  Whooping cough (pertussis) is a highly contagious disease of the human respiratory tract, which is caused by Bordetella pertussis. Reemerge of pertussis in some highly immunized populations and divergency in gene order among several B. pertussis strains promoted this research to study the change of pertussis toxin (PT) and lipopolysacharide levels in response to the different environments. Th...

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s of references provided in the position paper and GRADE tables  Amirthalingam G, Andrews N, Campbell H, Ribeiro S, Kara E, Donegan K, et al. Effectiveness of maternal pertussis vaccination in England: an observational study. Lancet 2014 Oct 25; 384(9953):1521-1528. BACKGROUND: In October, 2012, a pertussis vaccination programme for pregnant women was introduced in response to an outbreak acro...

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ژورنال

عنوان ژورنال: Clinical and Vaccine Immunology

سال: 2008

ISSN: 1556-6811,1556-679X

DOI: 10.1128/cvi.00391-07